Severity can range from mild to severe and can change daily, which can lead to lasting damage such as recurrent pancreatitis, diabetes mellitus and exocrine pancreatic insufficiency.¹
Pancreatitis is far more common in dogs than previously believed. Dogs with acute pancreatitis can present with a variety of clinical signs but also be subclinical. MCAI-5 has been introduced as an objective measure to aid in severity of disease. These are the 5 clinical signs associated with acute canine pancreatitis (ACP):2
DEHYDRATION
VOMITING
CRANIAL
ABDOMINAL PAIN
DECREASED
APPETITE
DECREASED
ACTIVITY
The prognosis of ACP is heavily dependent on the development of complications and early intervention.
Because severity can change daily, this leads to unexpectedly high patient costs due to hospitalization and supportive care.
This disease is stressful to the pet, the veterinarian, and the pet owner.
The prognosis of ACP is heavily dependent on the development of complications and early intervention.
Because severity can change daily, this leads to unexpectedly high patient costs due to hospitalization and supportive care.
This disease is stressful to the pet, the veterinarian, and the pet owner.
- Idiopathic (>90% of cases)
- Overweight (1.3x more likely to develop)
- Previous GI disease
- Ischemia/reperfusion
- Hypertriglyceridemia (schnauzers are 4x more likely to develop)
- Small breed
- Trauma
- Drugs/toxins
- Hypercalcemia
- Endocrine disease (hyperadrenocorticism, hypothyroidism, diabetes mellitus)
- Previous GI disease
- Ischemia/reperfusion
- Small breed
- Trauma
- Drugs/toxins
- Hypercalcemia
- Idiopathic (>90% of cases)
- Overweight (1.3x more likely to develop)
- Hypertriglyceridemia (schnauzers are 4x more likely to develop)
- Endocrine disease (hyperadrenocorticism, hypothyroidism, diabetes mellitus)
Schnauzer
Yorkshire Terrier
Poodle
Cocker Spaniel
Schnauzer
Yorkshire Terrier
Poodle
Cocker Spaniel
Schnauzer
Yorkshire Terrier
Poodle
Cocker Spaniel
Previously veterinarians could only treat the symptoms of this unpredictable disease.
PANOQUELL®-CA1 (fuzapladib sodium for injection) allows veterinarians to offer a solution which provides better results compared to current standard of care. Click below to find out how PANOQUELL®-CA1 works.
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1Cridge H, Scott N, Steiner JM. Risk Factors and Clinical Presentation in Dogs with Increased Serum Pancreatic Lipase Concentrations-A Descriptive Analysis. Animals (Basel). 2022 Jun 19;12(12):1581. doi: 10.3390/ani12121581. PMID: 35739917; PMCID: PMC9219463.
2Keany, KM, Fosgate, GT, Perry, SM, Stroup, ST, Steiner, JM. Serum concentrations of canine pancreatic lipase immunoreactivity and C-reactive protein for monitoring disease progression in dogs with acute pancreatitis. J Vet Intern Med. 2021; 35( 5): 2187- 2195. https://doi.org/10.1111/jvim.16218
3Cridge H, Lim SY, Algül H, Steiner JM. New insights into the etiology, risk factors, and pathogenesis of pancreatitis in dogs: Potential impacts on clinical practice. J Vet Intern Med. 2022 May;36(3):847-864. doi: 10.1111/